Research Articles
Advanced Characterization Techniques for Engineered Molecules: A Comprehensive Guide for Research and Drug Development
This article provides a comprehensive overview of the cutting-edge characterization techniques essential for the design, analysis, and optimization of engineered molecules.
Molecular Computing for Combinatorial Optimization: A New Paradigm for Drug Discovery and Biomedical Research
Combinatorial optimization problems are central to many challenges in drug discovery and biomedicine, yet often intractable for classical computers.
Harnessing Large Gene Clusters: Direct Cloning Strategies for Natural Product Discovery and Synthetic Biology
This article provides a comprehensive overview of the latest direct cloning strategies designed to capture large biosynthetic gene clusters (BGCs), crucial for mining novel natural products like antibiotics and chemotherapeutics.
Pathway Refactoring for Natural Product Synthesis: A Comprehensive Guide for Discovery and Optimization
This article provides a comprehensive overview of pathway refactoring, a pivotal synthetic biology tool for the discovery and optimized production of natural products.
CRISPR-Cas9 for BGC Cloning: Methods, Optimization, and Applications in Natural Product Discovery
This article provides a comprehensive overview of CRISPR-Cas9 technologies for cloning and manipulating biosynthetic gene clusters (BGCs) from microbial genomes.
AI-Driven Molecular Optimization: Revolutionizing Drug Discovery in 2025
This article explores the transformative impact of artificial intelligence on molecular optimization in drug discovery.
Navigating the Vast Combinatorics: Advanced Strategies for Molecular Optimization in Discrete Chemical Spaces
Molecular optimization in discrete chemical spaces represents a fundamental challenge in computational drug discovery and materials science.
Protein Side-Chain Conformation Prediction: Methods, Benchmarks, and Applications in Drug Discovery
Accurate prediction of protein side-chain conformations is a critical challenge in computational structural biology, with profound implications for protein design, docking, and understanding mutation effects.
Molecular Engineering Academic Programs: A Comprehensive Guide for Biomedical Researchers and Drug Development Professionals
This article provides a detailed exploration of academic programs in molecular engineering, tailored for researchers, scientists, and drug development professionals.
Navigating a Research Career in Molecular Engineering: From Foundational Principles to Cutting-Edge Applications
This article provides a comprehensive guide for researchers, scientists, and drug development professionals exploring career paths in molecular engineering.